This paper, based on a case study on 20 prefectures along Huai River eco-economic zone, uses their social-economic panel data from 2010—2015 as basis and applies entropy, comprehensive evaluation model and coordination model to measure land urbanization level and quality, and evaluates their coordination in order to give references for the healthy development of land urbanization of Huai River eco-economic zone. The result shows a rising 

 but fluctuating land urbanization level and quality,  due to substantial administrative adjustment. Land urbanization quality displays a decreasing ecological quality trend. Their coordination also is rising yearly, from poor coordination to high coordination, fast and then slow in rising rate. The provincial coordination difference and development level difference are quite similar and become small as development level rises, while the regional difference is outstanding, coordination of designed core cities is not good, unfavorable for performing urban function.